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Uplizna (inebilizumab-cdon)


Billing

Code: J1823

Description: Inj. inebilizumab-cdon, 1 mg

Unit: 1 mg

Payment: $473.513

Pay quarter: Q4 2023


Medicare history

Dosage and Frequency

Neuromyelitis optica spectrum disorder (NMOSD)

Initial:
• 300mg IV followed by another 300mg IV 2 weeks later

Subsequent:
• 300mg IV every 6 months

Calculate drug reimbursement


Total Reimbursement:

$142,053.90

(ASP: $134,013.11, Margin: $8,040.79)


Code:

J1823

# Units to bill:

300

Prior Authorization

Prior auth criteria for Uplizna may include but is not limited to:


1. The patient must have a confirmed diagnosis of neuromyelitis optica spectrum disorder (NMOSD) based on a positive AQP4-IgG serology test.

2. The patient must have had an inadequate response to at least two different disease-modifying treatments, including one treatment approved by the U.S. Food and Drug Administration (FDA) for NMOSD.

3. The patient must have experienced at least one episode of NMOSD-related vision loss or weakness in the past six months that required hospitalization or intravenous corticosteroids.

4. The patient must be 12 years of age or older.

5. The patient must not have any contraindications to Uplizna therapy, such as a history of hypersensitivity to albumin-containing products, or a history of severe allergic reactions to any components of Uplizna.


Insurance prior auth guidelines:

Aetna

United Healthcare

Anthem

Cigna


Billable NDCs

72677-0551-01

Uplizna (HORIZON)

300 MG


75987-0150-03

Uplizna (HORIZON THERAPEUTICS USA, INC.)

300 MG



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